Formulated to help clients deal with occasional sleeplessness and help support feelings of relaxation and reduced tension. Featuring the psychobiotic Bifidobacterium longum 1714™ with L-theanine and lemon balm extract.
At a glance
Zenbiome™ SLEEP is formulated to help clients deal with occasional sleeplessness, but can also help support feelings of relaxation and reduced tension.
- Supports sleep
- Promotes alpha brain waves
- Enhances vitality
Stress: The Modern Epidemic
According to a recent report from the American Institute of Stress, a large subset of the population is experiencing occasional stress that impacts their lifestyle. One in 10 Americans seek intervention to manage stress-related issues, including to support occasional mood changes, occasional sleeplessness, and lack of energy.
The Gut-Brain Axis and the Psychobiome
The gut-brain axis, a bidirectional communication between gut microbiota and the central nervous system (CNS), may play a role in cognitive function, digestion, and mood. Studies show that 80-90% of the fibers in the vagus nerve are linked to the gut, providing a physical link through which the gut microbiota communicate with the brain. Relatedly, the term psychobiome is used to describe the interaction between a person’s collective microbiome and his mental state. A diverse and balanced microbiome can help maintain the gut-brain axis. A psychobiotic is used to describe the commensal bacteria that play a role in the gut-brain axis and support brain health.
1714™: A Trail-blazing Psychobiotic
Our solution to supporting the psychobiome uses cutting-edge probiotic technology. 1714™, a unique strain of Bifidobacterium longum, is an up-and-coming psychobiotic that can help support the management of occasional stress and its biochemical expression within the human body. This psychobiotic exerts its effect by targeting the HPA axis to support healthy cortisol levels. 1714™ may support mental health, cognitive process, neurotransmitters, and overall feeling of well-being. In a 4-week human trial, 1714™ reduced perceived stress, improved memory performance, reduced mental fatigue, positively supported brainwave activity, and improved ability to handle occasional stress.
Ingredients and formula
Our new Zenbiome™ collection, powered by 1714™, has been specially developed to target the gut-brain axis and support clients with occasional stress, mild mood changes, low energy, feelings of occasional fatigue, and occasional sleeplessness.
BIFIDOBACTERIUM LONGUM (1714™)
L-THEANINE
LEMON BALM EXTRACT
Cognitive Support Studies
|
Form/Duration |
Study Details and Results |
Reference |
|---|---|---|
|
Bifidobacterium longum 1714® (Zenbiome Cope™ & Sleep™) 4 weeks |
Placebo-controlled study 22 participants 1714® strain supported cortisol levels and reduced perceived stress levels throughout the study compared to the placebo group. Significantly lower perceived stress levels in those participants taking B. longum 1714® compared to the placebo group. Bifidobacterium longum 1714® (Zenbiome Cope™ & Sleep™) |
DOI: 10.1038/ tp.2016.191 |
|
Bifidobacterium longum 1714® (Zenbiome Cope™ & Sleep™) 4 weeks |
Randomized, double-blinded, placebo-controlled trial 40 participants 1714® strain supported relaxation reduced stress, and enhanced mood Difference of neural activity change during resting state in theta band after 1714®- promoted theta brainwave activity at rest, compared to the placebo group. Difference of neural activity change during resting state in beta 2 band after 1714® supported body’s adaptation to beta 2 brain wave activity at rest, compared to the placebo group. |
DOI: 10.14309/ ajg.0000000000000203 |
(continued):
|
Form/Duration |
Study Details and Results |
Reference |
|---|
|
Bifidobacterium longum 1714® (Zenbiome Cope™ & Sleep™) 4 weeks |
Double-blind, randomized, placebo-controlled, repeated measures, cross-over design 20 participants Overall sleep quality and duration of sleep improved significantly in the probiotic treated group during exam stress compared with the placebo treated group. |
DOI: 10.1016/ j.bbih.2020.100174 |
|
Bifidobacterium longum 1714® and Bifidobacterium longum 35624® (Zenbiome Cope™ & Sleep™) 8 weeks |
Open label exploratory study 40 participants This exploratory open-label study found that 82% of subjects had significantly improved issues after 8 weeks, with 66% of subjects significantly improving after 4-weeks (issue severity score change of ≥ 50) in the moderate to severe group. The combination solution improved each of the individual issues (occasional abdominal discomfort, distension, bowel satisfaction), as well as an improvement in their quality of life. Participants in this group also had a significant improvement in their morning cortisol awakening response, a physiological biomarker of stress, after 4-weeks. |
DOI: 10.1111/nmo.14477 |
Dosing Instructions
Zenbiome COPE
Zenbiome SLEEP
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